Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer

Cancer progression is often paralleled by a decline in bone mass, raising risk of fracture. Concerns persist regarding anabolic interventions for skeletal protection, as these may inadvertently exacerbate neoplastic tissue expansion. Given bone's inherent mechanosensitivity, low intensity vibra...

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Main Authors: Pagnotti, Gabriel, Adler, Benjamin J., Green, Danielle E., Chan, Meilin E., Frechette, Danielle, Shroyer, Kenneth R., Beamer, Wesley G., Rubin, Janet, Rubin, Clinton T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412935/
https://ncbi.nlm.nih.gov/pubmed/22584009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2012.05.004
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