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Chromatin Alterations in Response to Forced Swimming Underlie Increased Prodynorphin Transcription

Antagonism of the kappa opioid receptor (KOR) has been reported to have anti-depressant-like properties. The dynorphin/KOR system is a crucial neurochemical substrate underlying the pathologies of addictive diseases, affective disorders and other disease states. However, the molecular underpinnings...

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Detalhes bibliográficos
Main Authors: Reed, Brian, Fang, Nancy, Blackwell-Mayer, Brandan, Chen, Shasha, Yuferov, Vadim, Zhou, Yan, Kreek, Mary Jeanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412925/
https://ncbi.nlm.nih.gov/pubmed/22698692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.06.006
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