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Tissue-specific DNA methylation of the human prodynorphin gene in post-mortem brain tissues and PBMCs

Dynorphins, the endogenous ligands for the kappa opioid receptor, are implicated in neuropsychiatric disorders through modulation of basal and stimuli-induced dopaminergic, glutamatergic and serotonergic tones. Expression of the prodynorphin gene (PDYN) is critical for rewarding properties of drugs...

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Bibliografski detalji
Glavni autori: Yuferov, Vadim, Nielsen, David A., Levran, Orna, Randesi, Matthew, Hamon, Sara, Ho, Ann, Morgello, Susan, Kreek, Mary Jeanne
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017726/
https://ncbi.nlm.nih.gov/pubmed/20808262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32833eecbc
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