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Tissue-specific DNA methylation of the human prodynorphin gene in post-mortem brain tissues and PBMCs
Dynorphins, the endogenous ligands for the kappa opioid receptor, are implicated in neuropsychiatric disorders through modulation of basal and stimuli-induced dopaminergic, glutamatergic and serotonergic tones. Expression of the prodynorphin gene (PDYN) is critical for rewarding properties of drugs...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017726/ https://ncbi.nlm.nih.gov/pubmed/20808262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32833eecbc |
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