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Ethnic diversity of DNA methylation in the OPRM1 promoter region in lymphocytes of heroin addicts

The μ-opioid receptor is the site of action of many endogenous opioids as well as opiates. We hypothesize that differences in DNA methylation of specific CpG dinucleotides between former severe heroin addicts in methadone maintenance treatment and control subjects will depend, in part, upon ethnicit...

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Main Authors: Nielsen, David A., Hamon, Sara, Yuferov, Vadim, Jackson, Colin, Ho, Ann, Ott, Jurg, Kreek, Mary Jeanne
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739429/
https://ncbi.nlm.nih.gov/pubmed/20237803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-010-0807-6
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