Exclusion of the 750-kb Genetically Unstable Region at Xq27 as a Candidate Locus for Prostate Malignancy in HPCX1-linked Families

Several linkage studies provided evidence for the presence of the hereditary prostate cancer locus, HPCX1, at Xq27-q28. The strongest linkage peak of prostate cancer overlies a variable region of ~750 kb at Xq27 enriched by segmental duplications (SDs), suggesting that the predisposition to prostate...

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Main Authors: Kouprina, Natalay, Lee, Nicholas CO, Pavlicek, Adam, Samoshkin, Alexander, Kim, Jung-Hyun, Lee, Hee-Sheung, Varma, Sudhir, Reinhold, William C, Otstot, John, Solomon, Greg, Davis, Sean, Meltzer, Paul S., Schleutker, Johanna, Larionov, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412920/
https://ncbi.nlm.nih.gov/pubmed/22733720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.21977
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