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tRNA genes protect a reporter gene from epigenetic silencing in mouse cells
It is a well-established fact that the tRNA genes in yeast can function as chromatin barrier elements. However, so far there is no experimental evidence that tRNA and other Pol III-transcribed genes exhibit barrier activity in mammals. This study utilizes a recently developed reporter gene assay to...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219543/ https://ncbi.nlm.nih.gov/pubmed/21822054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.16.17092 |
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