p100 Deficiency Is Insufficient for Full Activation of the Alternative NF-κB Pathway: TNF Cooperates with p52-RelB in Target Gene Transcription

BACKGROUND: Constitutive activation of the alternative NF-κB pathway leads to marginal zone B cell expansion and disorganized spleen microarchitecture. Furthermore, uncontrolled alternative NF-κB signaling may result in the development and progression of cancer. Here, we focused on the question how...

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Bibliografiska uppgifter
Huvudupphovsmän: Lovas, Agnes, Weidemann, Anja, Albrecht, Daniela, Wiechert, Lars, Weih, Debra, Weih, Falk
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412832/
https://ncbi.nlm.nih.gov/pubmed/22880094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042741
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