Peptidome Analysis of Cerebrospinal Fluid by LC-MALDI MS

We report on the analysis of endogenous peptides in cerebrospinal fluid (CSF) by mass spectrometry. A method was developed for preparation of peptide extracts from CSF. Analysis of the extracts by offline LC-MALDI MS resulted in the detection of 3,000–4,000 peptide-like features. Out of these, 730 p...

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Bibliografiske detaljer
Main Authors: Hölttä, Mikko, Zetterberg, Henrik, Mirgorodskaya, Ekaterina, Mattsson, Niklas, Blennow, Kaj, Gobom, Johan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412831/
https://ncbi.nlm.nih.gov/pubmed/22880031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042555
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