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JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny

BACKGROUND: It has been reported that the phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway regulates erythropoietin (EPO)-induced survival, proliferation, and maturation of early erythroid progenitors. Erythroid cell proliferation and survival have also been related to activation of the JA...

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Bibliographic Details
Main Authors: Cokic, Vladan P, Bhattacharya, Bhaskar, Beleslin-Cokic, Bojana B, Noguchi, Constance T, Puri, Raj K, Schechter, Alan N
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412720/
https://ncbi.nlm.nih.gov/pubmed/22676255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-116
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