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Synthesis of riboguanosine pentaphosphate ppprGpp (Magic Spot II) via a phosphotriester approach.

The bifunctional phosphorylating reagent O,O-bis[1-benzotriazolyl]phosphoromorpholidate was used to introduce a 5'-O-triphosphate and a 3'-O-diphosphate function in a partially protected riboguanosine. Pilot studies indicated that protection of the 2'-OH of ribonucleosides with the acid-labile tetra...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Schattenkerk, C, Wreesmann, C T, van der Marel, G A, van Boom, J H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1985
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341263/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4011437/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.10.3635
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