A Designed Zinc-finger Transcriptional Repressor of Phospholamban Improves Function of the Failing Heart

Selective inhibition of disease-related proteins underpins the majority of successful drug–target interactions. However, development of effective antagonists is often hampered by targets that are not druggable using conventional approaches. Here, we apply engineered zinc-finger protein transcription...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, H Steve, Liu, Dingang, Huang, Yan, Schmidt, Stefan, Hickey, Reed, Guschin, Dmitry, Su, Haili, Jovin, Ion S, Kunis, Mike, Hinkley, Sarah, Liang, Yuxin, Hinh, Linda, Spratt, S Kaye, Case, Casey C, Rebar, Edward J, Ehrlich, Barbara, Gregory, Philip D, Giordano, Frank J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412484/
https://ncbi.nlm.nih.gov/pubmed/22828502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.80
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak