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A Designed Zinc-finger Transcriptional Repressor of Phospholamban Improves Function of the Failing Heart
Selective inhibition of disease-related proteins underpins the majority of successful drug–target interactions. However, development of effective antagonists is often hampered by targets that are not druggable using conventional approaches. Here, we apply engineered zinc-finger protein transcription...
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| Hoofdauteurs: | , , , , , , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3412484/ https://ncbi.nlm.nih.gov/pubmed/22828502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.80 |
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