Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls

The control of RNA alternative splicing is critical for generating biological diversity. Despite emerging genome-wide technologies to study RNA complexity, reliable and comprehensive RNA-regulatory networks have not been defined. Here we used Bayesian networks to probabilistically model diverse data...

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Main Authors: Zhang, Chaolin, Frias, Maria A., Mele, Aldo, Ruggiu, Matteo, Eom, Taesun, Marney, Christina B., Wang, Huidong, Licatalosi, Donny D., Fak, John J., Darnell, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412410/
https://ncbi.nlm.nih.gov/pubmed/20558669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1191150
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