Dynamic antibody-binding properties in the pathogenesis of HIT

Rapid laboratory assessment of heparin-induced thrombocytopenia (HIT) is important for disease recognition and management. The utility of contemporary immunoassays to detect antiplatelet factor 4 (PF4)/heparin antibodies is hindered by detection of antibodies unassociated with disease. To begin to d...

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Detalhes bibliográficos
Main Authors: Sachais, Bruce S., Litvinov, Rustem I., Yarovoi, Serge V., Rauova, Lubica, Hinds, Jillian L., Rux, Ann H., Arepally, Gowthami M., Poncz, Mortimer, Cuker, Adam, Weisel, John W., Cines, Douglas B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412334/
https://ncbi.nlm.nih.gov/pubmed/22577175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-407262
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