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A new linkage for solid phase synthesis of oligodeoxyribonucleotides.

An aryl diisocyanate has been used to attach an appropriately protected 2'-deoxyribonucleoside bearing a free 3'-hydroxyl group, to a long chain alkylamine controlled pore glass support via a urethane moiety, in a simple two step procedure. This obviates the need for the preparation and sh...

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Detalles Bibliográficos
Autores principales: Sproat, B S, Brown, D M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1985
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC341208/
https://ncbi.nlm.nih.gov/pubmed/4000968
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