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Unwinding of supercoiled DNA by cis- and trans-diamminedichloroplatinum(II): influence of the torsional strain on DNA unwinding.

The effective unwinding angle, phi, for cis-diamminedichloroplatinum(II) (cis-DDP) and trans-DDP was determined by utilizing high resolution gel electrophoresis and supercoiled phi X174 RF DNA as a substrate. The effective unwinding angle was calculated by equating the reduction in mobility of the D...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Scovell, W M, Collart, F
Format: Artigo
Language:Inglês
Published: Oxford University Press 1985
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341201/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4039817/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.8.2881
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