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Epigenetic stability, adaptability, and reversibility in human embryonic stem cells

The stability of human embryonic stem cells (hESCs) is of critical importance for both experimental and clinical applications. We find that as an initial response to altered culture conditions, hESCs change their transcription profile for hundreds of genes and their DNA methylation profiles for seve...

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מידע ביבליוגרפי
Main Authors: Tompkins, Joshua D., Hall, Christine, Chen, Vincent Chang-yi, Li, Arthur Xuejun, Wu, Xiwei, Hsu, David, Couture, Larry A., Riggs, Arthur D.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411986/
https://ncbi.nlm.nih.gov/pubmed/22802633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209620109
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