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Modeling human cortical development in vitro using induced pluripotent stem cells

Human induced pluripotent stem cells (hiPSCs) are emerging as a tool for understanding human brain development at cellular, molecular, and genomic levels. Here we show that hiPSCs grown in suspension in the presence of rostral neuralizing factors can generate 3D structures containing polarized radia...

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Detalhes bibliográficos
Main Authors: Mariani, Jessica, Simonini, Maria Vittoria, Palejev, Dean, Tomasini, Livia, Coppola, Gianfilippo, Szekely, Anna M., Horvath, Tamas L., Vaccarino, Flora M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411972/
https://ncbi.nlm.nih.gov/pubmed/22761314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202944109
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