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The synthesis of oligonucleotides containing an aliphatic amino group at the 5' terminus: synthesis of fluorescent DNA primers for use in DNA sequence analysis.

A rapid and versatile method has been developed for the synthesis of oligonucleotides which contain an aliphatic amino group at their 5' terminus. This amino group reacts specifically with a variety of electrophiles, thereby allowing other chemical species to be attached to the oligonucleotide....

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Autors principals: Smith, L M, Fung, S, Hunkapiller, M W, Hunkapiller, T J, Hood, L E
Format: Artigo
Idioma:Inglês
Publicat: 1985
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC341163/
https://ncbi.nlm.nih.gov/pubmed/4000959
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