Impairment of GABAB receptor dimer by endogenous 14-3-3ζ in chronic pain conditions

In the central nervous system, the inhibitory GABAB receptor is the archetype of heterodimeric G protein-coupled receptors (GPCRs). However, the regulation of GABAB dimerization, and more generally of GPCR oligomerization, remains largely unknown. We propose a novel mechanism for inhibition of GPCR...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Laffray, Sophie, Bouali-Benazzouz, Rabia, Papon, Marie-Amélie, Favereaux, Alexandre, Jiang, Yang, Holm, Tina, Spriet, Corentin, Desbarats, Pascal, Fossat, Pascal, Le Feuvre, Yves, Decossas, Marion, Héliot, Laurent, Langel, Ulo, Nagy, Frédéric, Landry, Marc
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411072/
https://ncbi.nlm.nih.gov/pubmed/22692127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.161
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars