A Unique Sugar-binding Site Mediates the Distinct Anti-influenza Activity of Pig Surfactant Protein D

Pigs can act as intermediate hosts by which reassorted influenza A virus (IAV) strains can be transmitted to humans and cause pandemic influenza outbreaks. The innate host defense component surfactant protein D (SP-D) interacts with glycans on the hemagglutinin of IAV and contributes to protection a...

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Detalhes bibliográficos
Main Authors: van Eijk, Martin, Rynkiewicz, Michael J., White, Mitchell R., Hartshorn, Kevan L., Zou, Xueqing, Schulten, Klaus, Luo, Dong, Crouch, Erika C., Cafarella, Tanya R., Head, James F., Haagsman, Henk P., Seaton, Barbara A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411006/
https://ncbi.nlm.nih.gov/pubmed/22685299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.368571
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