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Monoclonal antibody-assisted structure-function analysis of the carbohydrate recognition domain of surfactant protein D

Surfactant protein D (SP-D) plays important roles in host defense against a variety of pathogens including influenza A virus (IAV). Ligand binding by SP-D is mediated by the trimeric neck and carbohydrate recognition domain (NCRD). We used monoclonal antibodies (mAbs) against human SP-D and a panel...

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Hlavní autoři: Hartshorn, Kevan L., White, Mitchell R., Rynkiewicz, Michael, Sorensen, Grith, Holmskov, Uffe, Head, James, Crouch, Erika C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951070/
https://ncbi.nlm.nih.gov/pubmed/20601494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00096.2010
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