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Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease
Emerging influenza viruses are a serious threat to human health because of their pandemic potential. A promising target for the development of novel anti-influenza therapeutics is the PA protein, whose endonuclease activity is essential for viral replication. Translation of viral mRNAs by the host r...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3410894/ https://ncbi.nlm.nih.gov/pubmed/22876176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002830 |
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