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Telmisartan directly ameliorates the neuronal inflammatory response to IL-1β partly through the JNK/c-Jun and NADPH oxidase pathways
BACKGROUND: Blockade of angiotensin II type 1 (AT(1)) receptors ameliorates brain inflammation, and reduces excessive brain interleukin-1 beta (IL-1β) production and release from cortical microglia. The aim of this study was to determine whether, in addition, AT(1) receptor blockade directly attenua...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3410820/ https://ncbi.nlm.nih.gov/pubmed/22642771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-102 |
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