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Minocycline ameliorates LPS-induced inflammation in human monocytes by novel mechanisms including LOX-1, Nur77 and LITAF inhibition

BACKGROUND: Minocycline exhibits anti-inflammatory properties independent of its antibiotic activity, ameliorating inflammatory responses in monocytes and macrophages. However, the mechanisms of minocycline anti-inflammatory effects are only partially understood. METHODS: Human circulating monocytes...

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Detalhes bibliográficos
Main Authors: Pang, Tao, Wang, Juan, Benicky, Julius, Saavedra, Juan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307860/
https://ncbi.nlm.nih.gov/pubmed/22306153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2012.01.011
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