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Loss of fused in sarcoma (FUS) promotes pathological Tau splicing
A subset of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) patients present pathological redistribution and aggregation of the nuclear protein fused in sarcoma (FUS) in the cytoplasm. Although FUS associates with the spliceosomal complex, no endogenous neuronal spli...
Gorde:
Egile Nagusiak: | , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Nature Publishing Group
2012
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3410390/ https://ncbi.nlm.nih.gov/pubmed/22710833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.90 |
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