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Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

A subset of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) patients present pathological redistribution and aggregation of the nuclear protein fused in sarcoma (FUS) in the cytoplasm. Although FUS associates with the spliceosomal complex, no endogenous neuronal spli...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Orozco, Denise, Tahirovic, Sabina, Rentzsch, Kristin, Schwenk, Benjamin M, Haass, Christian, Edbauer, Dieter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410390/
https://ncbi.nlm.nih.gov/pubmed/22710833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.90
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