Kindlin 2 forms a transcriptional complex with β-catenin and TCF4 to enhance Wnt signalling

Kindlin 2, as a focal adhesion protein, controls integrin activation. However, the association of Kindlin 2 with cancer-related signalling pathways is unknown. Here we identified a new direct interaction between Kindlin 2 and the active β-catenin. Importantly, Kindlin 2 forms a tripartite complex wi...

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Hlavní autoři: Yu, Yu, Wu, Junzhou, Wang, Yunling, Zhao, Ting, Ma, Bo, Liu, Yuqing, Fang, Weigang, Zhu, Wei-Guo, Zhang, Hongquan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
Scientific Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410388/
https://ncbi.nlm.nih.gov/pubmed/22699938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.88
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