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Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells
MicroRNAs (miRNAs) regulate most cellular functions, acting by posttranscriptionally repressing numerous eukaryotic mRNAs. They lead to translational repression, deadenylation and degradation of their target mRNAs. Yet, the relative contributions of these effects are controversial and little is know...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3410385/ https://ncbi.nlm.nih.gov/pubmed/22677978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.82 |
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