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Kinetic evidence that echinomycin migrates between potential DNA binding sites.
The hypothesis that echinomycin locates its preferred nucleotide sequences in DNA by a process of "shuffling" between potential binding sites has been tested. Immediately after reacting with calf thymus DNA the antibiotic is relatively weakly bound inasmuch as the complex dissociates quite...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1985
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC341017/ https://ncbi.nlm.nih.gov/pubmed/4000928 |
| Etiquetas: |
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