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Kinetic evidence that echinomycin migrates between potential DNA binding sites.

The hypothesis that echinomycin locates its preferred nucleotide sequences in DNA by a process of "shuffling" between potential binding sites has been tested. Immediately after reacting with calf thymus DNA the antibiotic is relatively weakly bound inasmuch as the complex dissociates quite rapidly w...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Nucleic Acids Res
Príomhchruthaitheoirí: Fox, K R, Waring, M J
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Oxford University Press 1985
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341017/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4000928/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.2.595
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