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Kinetic evidence that echinomycin migrates between potential DNA binding sites.

The hypothesis that echinomycin locates its preferred nucleotide sequences in DNA by a process of "shuffling" between potential binding sites has been tested. Immediately after reacting with calf thymus DNA the antibiotic is relatively weakly bound inasmuch as the complex dissociates quite...

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Detalhes bibliográficos
Main Authors: Fox, K R, Waring, M J
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC341017/
https://ncbi.nlm.nih.gov/pubmed/4000928
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