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Recognition of a cytosine base lesion by a human damage-specific DNA binding protein.

Sodium bisulfite reacts with cytosine and 5-methylcytosine, forming the 5,6-dihydrosulfonate adducts which deaminate to the uracil and thymine adducts, respectively. At alkaline pH, the sulfonate groups are then released, generating uracil and thymine. In DNA, the resulting G:U and G:T base mismatch...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Carew, J A, Feldberg, R S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1985
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340992/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4039815/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.1.303
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