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Recognition of a cytosine base lesion by a human damage-specific DNA binding protein.
Sodium bisulfite reacts with cytosine and 5-methylcytosine, forming the 5,6-dihydrosulfonate adducts which deaminate to the uracil and thymine adducts, respectively. At alkaline pH, the sulfonate groups are then released, generating uracil and thymine. In DNA, the resulting G:U and G:T base mismatch...
Gardado en:
| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1985
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340992/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4039815/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.1.303 |
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