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Protein−DNA binding in the absence of specific base-pair recognition

Until now, it has been reasonably assumed that specific base-pair recognition is the only mechanism controlling the specificity of transcription factor (TF)−DNA binding. Contrary to this assumption, here we show that nonspecific DNA sequences possessing certain repeat symmetries, when present outsid...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Afek, Ariel, Schipper, Joshua L., Horton, John, Gordân, Raluca, Lukatsky, David B.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260554/
https://ncbi.nlm.nih.gov/pubmed/25313048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410569111
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