DNA polymerase alpha and models for proofreading.
Using a modified system to measure fidelity at an amber site in phi X174, we have employed DNA polymerase alpha to test different mechanisms for proofreading. DNA polymerase alpha does not exhibit the characteristics of "kinetic proofreading" seen with procaryotic polymerases. Polymerase alpha shows...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1985
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| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340989/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2987791/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.1.261 |
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