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DNA polymerase alpha and models for proofreading.

Using a modified system to measure fidelity at an amber site in phi X174, we have employed DNA polymerase alpha to test different mechanisms for proofreading. DNA polymerase alpha does not exhibit the characteristics of "kinetic proofreading" seen with procaryotic polymerases. Polymerase alpha shows...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Abbotts, J, Loeb, L A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1985
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340989/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2987791/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.1.261
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