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Exonucleolytic proofreading by calf thymus DNA polymerase delta.
The fidelity of DNA synthesis by calf thymus DNA polymerase delta (pol delta) in vitro has been determined using an M13lacZ alpha nonsense codon reversion assay. Pol delta is highly accurate, producing on average less than 1 single-base substitution error for each 10(6) nucleotides polymerized. This...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1987
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305206/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3474631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.14.4865 |
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