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Exonucleolytic proofreading by calf thymus DNA polymerase delta.
The fidelity of DNA synthesis by calf thymus DNA polymerase delta (pol delta) in vitro has been determined using an M13lacZ alpha nonsense codon reversion assay. Pol delta is highly accurate, producing on average less than 1 single-base substitution error for each 10(6) nucleotides polymerized. This...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305206/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3474631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.14.4865 |
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