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Exonucleolytic proofreading by calf thymus DNA polymerase delta.

The fidelity of DNA synthesis by calf thymus DNA polymerase delta (pol delta) in vitro has been determined using an M13lacZ alpha nonsense codon reversion assay. Pol delta is highly accurate, producing on average less than 1 single-base substitution error for each 10(6) nucleotides polymerized. This...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kunkel, T A, Sabatino, R D, Bambara, R A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
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Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305206/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3474631/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.14.4865
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