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Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony

The current trend of antimony (Sb) unresponsiveness in the Indian subcontinent is a major impediment to effective chemotherapy of visceral leishmaniasis (VL). Although contributory mechanisms studied in laboratory raised Sb-R parasites include an up regulation of drug efflux pumps and increased thio...

詳細記述

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書誌詳細
主要な著者: Mandal, G., Wyllie, S., Singh, N., Sundar, S., Fairlamb, A.H., Chatterjee, M.
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409873/
https://ncbi.nlm.nih.gov/pubmed/17612420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0031182007003150
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