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Bicyclic Cyclohexenones as Inhibitors of NF-κB Signaling
[Image: see text] A series of structurally simplified cryptocaryone analogues were synthesized by a facile Pd-catalyzed acetoxylation of alkyne-tethered cyclohexadienones and evaluated as inhibitors of NF-κB signaling. Compounds 10 and 11 were found to possess low micromolar inhibitory properties to...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American
Chemical Society
2012
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409840/ https://ncbi.nlm.nih.gov/pubmed/22866208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300034a |
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