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Catch and Release DNA Decoys: Capture and Photochemical Dissociation of NF-κB Transcription Factors

Catch and Release DNA Decoys (CRDDs) are a new class of non-natural DNA probes that capture and dissociate from DNA-binding proteins using a light trigger. Photolytic cleavage of non-natural nucleobases in the CRDD yields abasic sites and truncation products that lower the affinity of the CRDD for i...

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Udgivet i:ACS Chem Biol
Main Authors: Struntz, Nicholas B., Harki, Daniel A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941104/
https://ncbi.nlm.nih.gov/pubmed/27054264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00130
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