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Yeast genetic selections to optimize RNA decoys for transcription factor NF-κB
In vitro-selected RNA aptamers are potential inhibitors of disease-related proteins. Our laboratory previously isolated an RNA aptamer that binds with high affinity to human transcription factor NF-κB. This RNA aptamer competitively inhibits DNA binding by NF-κB in vitro and is recognized by its tar...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153025/ https://ncbi.nlm.nih.gov/pubmed/12637683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0736013100 |
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