Caveolin-1 deficiency causes cholesterol dependent mitochondrial dysfunction and apoptotic susceptibility

Caveolins (CAV) are essential components of caveolae; plasma membrane invaginations with reduced fluidity, reflecting cholesterol accumulation [1]. CAV proteins bind cholesterol, and CAV’s ability to move between cellular compartments helps control intracellular cholesterol fluxes [1–3]. In humans,...

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Hauptverfasser: Bosch, Marta, Marí, Montserrat, Herms, Albert, Fernández, Ana, Fajardo, Alba, Kassan, Adam, Giralt, Albert, Colell, Anna, Balgoma, David, Barbero, Elisabet, González-Moreno, Elena, Matias, Nuria, Tebar, Francesc, Balsinde, Jesús, Camps, Marta, Enrich, Carlos, Gross, Steven P., García-Ruiz, Carmen, Pérez-Navarro, Esther, Fernández-Checa, José C., Pol, Albert
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409647/
https://ncbi.nlm.nih.gov/pubmed/21497090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.03.030
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