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Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains

Control of lipid droplet (LD) nucleation and copy number are critical, yet poorly understood, processes. We use model peptides that shift from the endoplasmic reticulum (ER) to LDs in response to fatty acids to characterize the initial steps of LD formation occurring in lipid-starved cells. Initiall...

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Detalhes bibliográficos
Main Authors: Kassan, Adam, Herms, Albert, Fernández-Vidal, Andrea, Bosch, Marta, Schieber, Nicole L., Reddy, Babu J.N., Fajardo, Alba, Gelabert-Baldrich, Mariona, Tebar, Francesc, Enrich, Carlos, Gross, Steven P., Parton, Robert G., Pol, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871434/
https://ncbi.nlm.nih.gov/pubmed/24368806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201305142
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