The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses

Infiltration of specialized immune cells regulates the growth and survival of neoplasia. Here, in a survey of public whole genome expression datasets we found that the gene for chemerin, a widely expressed endogenous chemoattractant protein, is down-regulated in melanoma as well as other human tumor...

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Autors principals: Pachynski, Russell K., Zabel, Brian A., Kohrt, Holbrook E., Tejeda, Nicole M., Monnier, Justin, Swanson, Christina D., Holzer, Alison K., Gentles, Andrew J., Sperinde, Gizette V., Edalati, Abdolhossein, Hadeiba, Husein A., Alizadeh, Ash A., Butcher, Eugene C.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2012
Matèries:
Brief Definitive Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409495/
https://ncbi.nlm.nih.gov/pubmed/22753924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112124
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