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The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses

Infiltration of specialized immune cells regulates the growth and survival of neoplasia. Here, in a survey of public whole genome expression datasets we found that the gene for chemerin, a widely expressed endogenous chemoattractant protein, is down-regulated in melanoma as well as other human tumor...

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Detalhes bibliográficos
Main Authors: Pachynski, Russell K., Zabel, Brian A., Kohrt, Holbrook E., Tejeda, Nicole M., Monnier, Justin, Swanson, Christina D., Holzer, Alison K., Gentles, Andrew J., Sperinde, Gizette V., Edalati, Abdolhossein, Hadeiba, Husein A., Alizadeh, Ash A., Butcher, Eugene C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409495/
https://ncbi.nlm.nih.gov/pubmed/22753924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112124
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