Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance

Central tolerance can be mediated by peripheral dendritic cells (DCs) that transport innocuous antigens (Ags) to the thymus for presentation to developing T cells, but the responsible DC subsets remain poorly defined. Immature plasmacytoid DCs (pDCs) express CCR9, a chemokine receptor involved in mi...

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Main Authors: Hadeiba, Husein, Lahl, Katharina, Edalati, Abdolhossein, Oderup, Cecilia, Habtezion, Aida, Pachynski, Russell, Nguyen, Linh, Ghodsi, Asma, Adler, Sarah, Butcher, Eugene C.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315699/
https://ncbi.nlm.nih.gov/pubmed/22444632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.01.017
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