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Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance

Central tolerance can be mediated by peripheral dendritic cells (DCs) that transport innocuous antigens (Ags) to the thymus for presentation to developing T cells, but the responsible DC subsets remain poorly defined. Immature plasmacytoid DCs (pDCs) express CCR9, a chemokine receptor involved in mi...

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書誌詳細
主要な著者: Hadeiba, Husein, Lahl, Katharina, Edalati, Abdolhossein, Oderup, Cecilia, Habtezion, Aida, Pachynski, Russell, Nguyen, Linh, Ghodsi, Asma, Adler, Sarah, Butcher, Eugene C.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315699/
https://ncbi.nlm.nih.gov/pubmed/22444632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.01.017
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