Pancreatic Damage in Fetal and Newborn Cystic Fibrosis Pigs Involves the Activation of Inflammatory and Remodeling Pathways

Pancreatic disease has onset in utero in humans with cystic fibrosis (CF), and progresses over time to complete destruction of the organ. The exact mechanisms leading to pancreatic damage in CF are incompletely understood. Inflammatory cells are present in the pancreas of newborn pigs with CF (CF pi...

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Detalhes bibliográficos
Main Authors: Abu-El-Haija, Maisam, Ramachandran, Shyam, Meyerholz, David K., Abu-El-Haija, Marwa, Griffin, Michelle, Giriyappa, Radhamma L., Stoltz, David A., Welsh, Michael J., McCray, Paul B., Uc, Aliye
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409440/
https://ncbi.nlm.nih.gov/pubmed/22683312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.04.024
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