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Pancreatic Damage in Fetal and Newborn Cystic Fibrosis Pigs Involves the Activation of Inflammatory and Remodeling Pathways

Pancreatic disease has onset in utero in humans with cystic fibrosis (CF), and progresses over time to complete destruction of the organ. The exact mechanisms leading to pancreatic damage in CF are incompletely understood. Inflammatory cells are present in the pancreas of newborn pigs with CF (CF pi...

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Hlavní autoři: Abu-El-Haija, Maisam, Ramachandran, Shyam, Meyerholz, David K., Abu-El-Haija, Marwa, Griffin, Michelle, Giriyappa, Radhamma L., Stoltz, David A., Welsh, Michael J., McCray, Paul B., Uc, Aliye
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409440/
https://ncbi.nlm.nih.gov/pubmed/22683312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.04.024
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